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Antigen presentation is essential for the activation and clonal selection of?
Wiki User
∙ 13y ago
T cells
Wiki User
∙ 13y ago
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Alloreactivity is a positive selection step or negative selection step?
Neither. Alloreactivity has to do with a lymphocytes reacting to a foreign antigen. Positive and negative selection are processes of central tolerance which is to say that they deal with a T cell's ability to bind self-antigen.
What is clonal selection responsible for?
Clonal selection is responsible for the proliferation of clones of effector and memory cells specific for an encountered antigen
What area is antigen challenge and clonal selection most likely to occur?
Lymph node
Which of the following is not an antigen that may be found on the surface of an erythrocyte a A antigen b B antigen c O antigen d Rh antigen?
A antigen
What is the clonal selection theory as it applies to B cells?
1. An antigen presenting cell presents antigen on Class II MHC to a Helper T cell activating it 2. At the same time a B cell that has taken up and degraded the same pathogen displays antigen on its class II 3. The activated helper T cell binds to the B cell releasing cytokines and activating it 4. The activated B cell proliferates and differentiates into: 1) memory B cells 2) antibody-secreting plasma cells that produce antibodies specific for the pathogen
The binding of an antigen to an antibody can result in?
neutralization of the antigen, agglutination or precipitation, and complement activation.
What do dendrictic cell do?
antigen processing and presentation
Is T cell activation antigen specific?
Yes. The first signal that a T cell receives from an antigen presenting cell (dendritic cell) is MHC presenting an antigen (foreign peptide). This gives the T cell specificity to this antigen.
Alloreactivity is a positive selection step or negative selection step?
Neither. Alloreactivity has to do with a lymphocytes reacting to a foreign antigen. Positive and negative selection are processes of central tolerance which is to say that they deal with a T cell's ability to bind self-antigen.
When IL-2 is secreted by antigen-specific T cells activated due to presentation of antigen by APCs What happens to naive antigen-nonspecific T cells in the vicinity?
They proliferate due to their exposure to IL-2
What is clonal selection responsible for?
Clonal selection is responsible for the proliferation of clones of effector and memory cells specific for an encountered antigen
